ANTI-M1 IMMUNOGLOBULINS AND IMMUNODIAGNOSTIC REAGENTS TO DETECT SARS-COV-2 ANTIGENS

INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Ruby Anne N. King, Dr. Fresthel Monica M. Climacosa, Dr. Maria Isabel C. Idolor, Danica S. Ching   DESCRIPTION The invention provides anti-peptide immunoglobulins that recognize non-glycosylated epitopes of SARS-CoV-2 membrane glycoprotein, cognate oligopeptide-based immunogenic constructs suitable for producing said immunoglobulins, and methods for producing and utilizing said constructs and immunoglobulins.   […]

M1 IMMUNODIAGNOSTIC REAGENTS TO DETECT ANTIBODIES AGAINST SARS-COV-2

INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Ruby Anne N. King, Dr. Fresthel Monica M. Climacosa   DESCRIPTION The invention provides peptide-based antigenic constructs comprising a plurality of monomeric units and recognized by immunoglobulins that bind to protein epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); methods for producing said constructs using peptide precursors that comprise […]

ANTIGENIC CONSTRUCTS

INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Cecile C. Dungog   DESCRIPTION The invention provides for the use of epitope-modifying chemical crosslinking agents to produce surface-binding antigenic constructs for detecting epitope-specific antibodies, said agents abrogating molecular recognition underlying said epitope-specific antibody detection when used in excess.   VALUE PROPOSITION Peptide-based materials are biodegradable and environmentally benign. […]

PEPTHEMATICS

Peptides and Modified Blood Products for Diagnosis and Treatment of Coagulopathic, Inflammatory and Infectious Conditions   INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Ruby Anne N. King, Dr. Fresthel Monica M. Climacosa, Dr. Bobbie Marie M. Santos   DESCRIPTION The invention provides peptide derivatives and modified blood products for evaluating and modulating blood plasma coagulation activity, complement function, […]

Genetics of Lupus

DESCRIPTION The IP provides for a simple genetic testing method, either sequencing or using a probe-based platform, which involves the determination of the association of selected single nucleotide polymorphisms (SNPs) that are correlated with the risk of Systemic lupus erythematosus (SLE). Potentially, this IP is useful in the setting of preventive measures and monitoring, screening […]

DESCRIPTION The intellectual property (IP) is a Crude Pollen Extract used for diagnostics (skin allergy testing), and therapeutic (specific allergen immunotherapy) use. It includes 3 weeds, 15 grass, and 5 tree local pollen extracts currently solely manufactured by the Section of Allergy and Immunology (SAF) of Philippine General Hospital (PGH). These allergen extracts are all […]