ANTI-S1 IMMUNOGLOBULINS AND IMMUNODIAGNOSTIC REAGENTS TO DETECT SARS-COV-2 ANTIGENS

INVENTORS Dr. Salvador Eugenio Caoili, Dr. Fresthel Monica Climacosa, Dr. Ruby Anne King, Riziel Hannah Aguimatang, Ayra Patrice Espiritu   DESCRIPTION The invention provides anti-peptide immunoglobulins that recognize epitopes of SARS-CoV-2 spike glycoprotein subdomain SD2, cognate oligopeptide-based immunogenic constructs suitable for producing said immunoglobulins, and methods for producing and utilizing said constructs and immunoglobulins.   VALUE PROPOSITION New materials […]

ANTI-M1 IMMUNOGLOBULINS AND IMMUNODIAGNOSTIC REAGENTS TO DETECT SARS-COV-2 ANTIGENS

INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Ruby Anne N. King, Dr. Fresthel Monica M. Climacosa, Dr. Maria Isabel C. Idolor, Danica S. Ching   DESCRIPTION The invention provides anti-peptide immunoglobulins that recognize non-glycosylated epitopes of SARS-CoV-2 membrane glycoprotein, cognate oligopeptide-based immunogenic constructs suitable for producing said immunoglobulins, and methods for producing and utilizing said constructs and immunoglobulins.   […]

M1 IMMUNODIAGNOSTIC REAGENTS TO DETECT ANTIBODIES AGAINST SARS-COV-2

INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Ruby Anne N. King, Dr. Fresthel Monica M. Climacosa   DESCRIPTION The invention provides peptide-based antigenic constructs comprising a plurality of monomeric units and recognized by immunoglobulins that bind to protein epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); methods for producing said constructs using peptide precursors that comprise […]

ANTIGENIC CONSTRUCTS

INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Cecile C. Dungog   DESCRIPTION The invention provides for the use of epitope-modifying chemical crosslinking agents to produce surface-binding antigenic constructs for detecting epitope-specific antibodies, said agents abrogating molecular recognition underlying said epitope-specific antibody detection when used in excess.   VALUE PROPOSITION Peptide-based materials are biodegradable and environmentally benign. […]

PEPTHEMATICS

Peptides and Modified Blood Products for Diagnosis and Treatment of Coagulopathic, Inflammatory and Infectious Conditions   INVENTORS: Dr. Salvador Eugenio C. Caoili, Dr. Ruby Anne N. King, Dr. Fresthel Monica M. Climacosa, Dr. Bobbie Marie M. Santos   DESCRIPTION The invention provides peptide derivatives and modified blood products for evaluating and modulating blood plasma coagulation activity, complement function, […]

POWERED AIR PURIFYING RESPIRATOR “PAPR”

INVENTORS: Dr. Samuel Grozman; Dr. Philip Fullante; Dr. Magdaleno R. Vasquez, Jr.; Dr. Miguel Sandino Aljibe; Engr. Lance Tristan Pengson   DESCRIPTION The recent outbreak of the COVID-19 pandemic has increased the global demand for personal protective equipment, including PAPR’s. In the Philippines, the lack of personal protective equipment is still a problem in some medical facilities. The […]

RXBOX TELEMETRY SYSTEM

INVENTORS: Dr. Luis Sison; Dr. Portia Fernandez-Marcelo, MD, MPH; Dr. Geohari Hamoy, MD, MPH   DESCRIPTION RxBox Telemetry System (Telemetry) is a biomedical device that allows Health Care Workers specifically nurses to remotely monitor the vital signs of patients in COVID Wards through a monitoring dashboard, it uses the existing RxBox device with the newly developed telemetry software […]

DIGITAL HISTOLOGIC ANALYSIS SOFTWARE FOR HIRSCHSPRUNG’S DISEASE

INVENTORS: Dr. Alvin Caballes; Prof. Prospero C. Naval, Jr.; Dr. Mark Angelo Ang; Mr. Martin Roy Nabus   DESCRIPTION Hirschsprung Disease is a congenital disorder in the colon that is characterized by the absence of nerve ganglion cells in the diseased tissue. The diagnosis of this disease depends on the histologic evaluation of multiple biopsies to determine the […]

CLEANINTUBATE: LARYNGOSCOPE BLADE DISINFECTING DEVICE

INVENTORS: Dr. Catherine Co; Engr. Jason Pechardo; Dr. Ma. Teresita Aspi; Prof. Ed Magdaluyo; Engr. Edgar Argote   DESCRIPTION The laryngoscope is a medical equipment used to visualize the opening between the vocal cords to secure the airway during intubation for patients requiring assistance in breathing.  The laryngoscope blade used requires at minimum high-level disinfection, which is a manual […]

ANTIMICROBIAL & ANTIBIOFILM ORAL PREPARATIONS

INVENTORS: Dr. Erna C. Arollado & Dr. Angelina Atienza University of the Philippines – Manila   DESCRIPTION Naturally-derived compositions from the plant CP against resistant endodontic pathogens and other anti-microbial and anti-biofilm applications.   VALUE PROPOSITION It is a natural product Pre-Clinical studies demonstrate safety for use No residual side effects   MARKET APPLICATIONS AND […]